If you’re feeling safe about travel and are looking for new lodging choices, keep these Midwest hotels on your short list. Some are already open; others plan to open soon.

By Ginger Crichton
Updated October 06, 2020

When hotels’ long-planned openings end up coinciding with a pandemic, some forge ahead anyway. Check out these Midwest lodgings that have opened this year or are scheduled to open soon:


Lytle Park Hotel
Aaron Conway

The 106-room Lytle Park Hotel opened in June inside a 1909 building. The design brings in the vibe of the surrounding Lytle Park with a vaulted glass ceiling, plenty of greenery and nature-inspired decor. A four-season rooftop patio overlooks the park, downtown Cincinnati and the Ohio River; guests can also enjoy a lobby bar and fine-dining Italian restaurant Subito.

Kinley Lobby
Courtesy of The Kinley Hotel

The Kinley Hotel, located between downtown and the Over-the-Rhine neighborhood, is slated to open October 22 in the historic Denton Building, built in 1916. The 94 guest rooms and public spaces shimmer in blue and gold tones accented with distinctive wallpaper and art; on-site restaurant Khora will focus on pasta, with grains sourced from the Ohio Valley.  The hotel is working with Cincinnati Art Underground to curate local art pieces and a custom-designed mural for the lobby.

Carmel, Indiana

Hotel Carmichael lobby bar
Courtesy of Hotel Carmichael

Hamilton County’s first boutique hotel, the 122-room Carmichael, opened in September in downtown Carmel next to The Great American Songbook Foundation and The Center for Performing Arts. The six-story hotel reflects the neoclassical design of the Palladium, the largest of the performing arts center’s three venues, with a grand piano in the lobby bar and chandeliers throughout guest spaces. Live music is planned every day.


Bottleworks Hotel rendering
Courtesy of Bottleworks Hotel

Work continues on the Bottleworks Hotel, a 139-room boutique lodging inside a 1930s-era Coca-Cola bottling factory. The hotel, tentatively scheduled to open late this year, is part of the first phase of the $300 million Bottleworks District project, which will include a food hall and movie theater as well as retail and office space in and around the Art Deco bottling plant.

Kansas City, Missouri

Tudor Ballroom, Hotel Kansas City
Courtesy of Hotel Kansas City

Hotel Kansas City opened in October in the 1922 building that used to house the Kansas City Club. Renovation of the Gothic Revival-style building preserved touches like stained glass and walnut accents in the Tudor Ballroom while also delivering 144 modern guest rooms, restaurants and bars. The 15-story building, which has a limestone and brick exterior with terracotta embellishments, is on the National Register of Historic Places.


Peregrine Hotel Lobby
Courtesy of The Peregrine Hotel Omaha

Expected to open by early 2021, The Peregrine Hotel Omaha is named for a falcon-breeding program on the adjacent WoodmenLife Tower. Watch for the birds from the hotel’s rooftop bar (the city’s first). Inside, the Hilton Curio Collection property has a chic, Art Deco-meets-woodsy feel, with avian art and a six-story mural of the namesake species, visible exclusively from Falcon View guest rooms.

Kimpton Cottonwood Hotel garden lounge
Courtesy of Kimpton Cottonwood Omaha

A mile and a half west of The Peregrine, in the Blackstone District, Kimpton Cottonwood Hotel is also due to open later this year. Restored to its 1916 glory, the lodging (formerly The Blackstone Hotel) will greet guests with a grand marble staircase, garden lounge with pool views, and 205 luxe rooms and suites.


Nobu Hotel Chicago, in the West Loop, opened over the summer. The 115 rooms and suites reflect a mix of sleek modern design and old-world Japanese influences. Rooftop dining will eventually by complemented by on-site Nobu Restaurant, with Japanese cuisine. 

21c Museum Hotel opened a 297-room hotel in February in the River North / Magnificent Mile neighborhood. It closed in March due to the pandemic but reopened in September. Like others in the 21c collection, it features a free contemporary art museum that’s open to the public as well as original artwork in the rooms. (21c has also announced hotels opening in 2021 or 2022 in Des Moines and St. Louis.)

Amana Colonies, Iowa 

Courtesy of Hotel Millwright

Hotel Millwright opened October 1 in the revitalized Amana Woolen Mill complex, part of the legacy of seven communal villages established in 1855. The 65-room hotel is the area’s first boutique lodging and includes a restaurant, two bars and conference center. Custom Amana textiles and historical art bring local touches to each room.

St. Louis

Live! by Loews Ballpark Village opened in February, only to shut down because of pandemic concerns in March, but the 216-room, baseball-theme hotel—a partnership with the St. Louis Cardinals—reopened in June.

The former 91-room Hotel Majestic is scheduled to open late this year as a Marriott-branded Le Méridien after renovations. Another Le Méridien opened in the Clayton neighborhood.