What to do
The District The university’s youthful energy feeds this area, known for more than 110 shops, restaurants and galleries—plus live music. discoverthedistrict.com
University of Missouri Mizzou has a distinctly historical feel, with 18 buildings on the National Register of Historic Places. The grounds are a designated botanical garden. Free guided tours. (800) 856-2181; missouri.edu
Where to eat
Lucy’s Corner Cafe For breakfast, try the pancakes that drape over the edge of your plate and biscuits with sausage gravy. See reviews and ratings. (573) 875-1700
Shakespeare’s Pizza Close to the Mizzou campus, the original location is known to pile on the toppings. See reviews and ratings. (573) 449-2454; shakespeares.com
Where to stay
Yates House Bed and Breakfast A two-story, redbrick inn fits right in among the antebellum homes in Rocheport (12 miles west); you’d never know it was built in 1991. Breakfast includes crème brûlée French toast. From $189. See reviews and ratings. (573) 698-2129; yateshouse.com
For information: Columbia Convention and Visitors Bureau (800) 652-0987; visitcolumbiamo.com


