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What to do
Crisp Museum Highlights include a video overview of the region, architectural history, and an art gallery. (573) 651-2260; semo.edu/museum
Where to eat
My Daddy’s Cheesecake Bakery and Cafe Come for bakery treats or any meal of the day, but don’t leave without a slice of cheesecake. Mississippi Mud is a fave. See reviews and ratings. (573) 335-6660; mydaddyscheesecake.com
Where to stay
Rose Bed Inn With an on-site spa, art gallery and chef-prepared breakfast, the term “B&B” doesn’t do it justice. From $125. See reviews and ratings. (866) 767-3233; rosebedinn.com
For information: Cape Girardeau Convention and Visitors Bureau (800) 777-0068; visitcape.com
