As the first university established west of the Mississippi, "Mizzou" in Columbia (population 100,000) has a distinctly historic feel, with 18 of its buildings on the National Register of Historic Places. The University of Missouri's grounds are also a designated botanic garden, with more than 6,500 trees. The gardens and buildings (including The Residence) around the David R. Francis Quadrangle should not be missed. Free, guided tours last an hour (800/856-2181; missouri.edu).
University of Missouri
Columbia Convention and Visitors Bureau
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