Two-day Itineraries | Midwest Living
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Two-day Itineraries

Explore the Midwest with the help of our two-day itineraries, ideal for a weekend or overnight getaway. Find itineraries for big cities, small towns and scenic drives in Michigan, Minnesota, Wisconsin, Illinois, Iowa, Indiana, Ohio, Kansas, Missouri, Nebraska, South Dakota and North Dakota.

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The Great River Road takes the name Meeting of the Great Rivers National Scenic Byway between Alton and Grafton, north of St. Louis.
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The “Waterpark Capital of the World” ranks as one of the most kid-friendly vacation spots in the Heartland, with more than 200 water slides and one of the world's only upside-down wooden roller...
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The state capital tempts with locavore eateries, outdoor rec, museums—and Badger fandom.
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Rapid City and the Badlands (75 miles apart on Interstate-90) combine for a great list of must-do stops.
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Covered bridges and lush farmland give way to bountiful vineyards south of Lake Erie. Things to do in Ohio's wine country include the Bridges Driving Tour and the Grand River Canoe Livery and...
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The Queen City’s crown jewels include pro sports, a bounty of great museums and a standout zoo.
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Cowboy-themed, family-oriented Medora makes a great base for a visit to Theodore Roosevelt National Park.
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This reservoir in central Missouri has a rep as a full-throttle boating vacation destination.
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Lakeside family fun defines Brainerd Lakes, 130 miles north of the Twin Cities.
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The other “twin,” Saint Paul’s energetic neighborhoods give Minnesota's state capital a personality all its own.

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