Two-day Itineraries | Midwest Living

Two-day Itineraries

Explore the Midwest with the help of our two-day itineraries, ideal for a weekend or overnight getaway. Find itineraries for big cities, small towns and scenic drives in Michigan, Minnesota, Wisconsin, Illinois, Iowa, Indiana, Ohio, Kansas, Missouri, Nebraska, South Dakota and North Dakota.

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The Cuyahoga Valley Scenic Railroad showcases the scenery between Cleveland and Akron.
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Small towns with personality dot the Flint Hills Scenic Byway through our nation’s largest remaining tallgrass prairie.
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History infuses almost everything in Springfield. Much of Abraham Lincoln’s past lives on here, but beyond that, you’ll find a carillon, classic eats and ghost stories.
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A city known for its lovely art glass, Toledo Mud Hens baseball team and pretty architecture also boasts a stunning cathedral, formal gardens and a great zoo.
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The thrill of NASCAR racing, along with a lively town square and the Iowa’s most famous cheese, bring visitors to Newton, a half-hour east of Des Moines.
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Distinctive museums, eclectic shops and local flavors are attractions in Ames, Iowa, home of Iowa State University.
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Along the Cannon River, 45 minutes south of the Twin Cities, Northfield and Faribault draw visitors with Victorian downtowns, funky boutiques, cafes, riverside bike trails and parks, and cultural...
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An appealing mix of culture and nature flow through Winona—a treasure of a city sitting on a giant Mississippi River sandbar.
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Known for iconic pottery and handcrafted boots, Red Wing’s well-preserved downtown and Mississippi River and bluffs make it one of Minnesota’s most romantic weekend getaways.
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Home to the world renowned Mayo Clinic, Rochester (population: 100,500) was providing top-notch TLC long before medical tourism became a trend. It also has hospitality down to a science, welcoming...

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