Famous for its signature clock tower, this Best Western hotel and conference center also houses the family-friendly CoCo Key Water Resort. The 65,000-square-foot indoor water park features whirlpools, slides, an "adventure river" and an activity pool with an animated backdrop showing a coral reef. The hotel has 245 guest rooms along with indoor and outdoor pools, tennis courts, a fitness center and 30,000 square feet of space for special events. Rooms are $169 to $279 a night.