When this opulent, Italian Renaissance-style hotel was built in 1924, it was not only the tallest building in Detroit but the tallest hotel in the world. In its heyday, the hotel hosted such illustrious guests as presidents Herbert Hoover and Harry Truman, singer Frank Sinatra and baseball great Lou Gehrig. Today the Westin Book Cadillac is on the National Registry of Historic Places, and a $200 million restoration in 2008 returned it to its previous glory. Despite its pedigree, the hotel's 453 rooms boast a clean, minimalist look with lots of natural light, thanks to windows lining the building's facade. You'll find plenty of amenities, including a 13-inch pillow top, 42-inch plasma televisions, laptop safes, in-room spa services and a gym and swimming pool, but not free Internet. Start your morning at the WBC Gourmet Grab & Go for coffee and pastries, and end your evening at Chef Michael Symon's innovative Roast. Or sample the eclectic fare at 24 Grille, enjoy breakfast or lunch in The Boulevard Room, and stop by The Motor Bar, just off the lobby, for creative cocktails and light bites. Rooms from $169. Located in the central part of downtown Detroit, it's relatively close to the MGM Grand Casino, Detroit Lions' Ford Field, Detroit Tigers' Comerica Park, Fox Theater, Gem Theatre, The Second City Detroit comedy theater and the Music Hall Center for the Performing Arts.